MigraSpray, a OTC migraine relief product designed in San Diego, California, is ingested through sublingual administration. This process allows for the rapid introduction of the drug into the bloodstream via the blood vessels, which are located in the highly vascularized mucous membrane under the tongue.
MigraSpray contains only natural, standardized ingredients, and is made by strictly adhering to Good Manufacturing Practices (GMP). There have been no reported side effects and no incidents of drug interaction with any over-the-counter or prescription medications. The active ingredients include polyporus, goldenseal, dandelion and feverfew, its primary component. For centuries, feverfew has been used to treat a variety of ailments including headaches, rheumatic aches, abdominal pain and menstrual cramps. Studies have shown that feverfew acts as a natural anti-inflammatory, suppressing inflammation occurring in the cerebral blood vessels — believed to contribute to migraine headache symptoms.
The administration of sublingual drugs offers improved drug bioavailability and rapid metabolization. This allows for a more complete absorption and maximizes the benefits for the patient by permitting more precise dosage control. Sublingual drug administration is a developing field for the administration of many vitamins and minerals, which are found to be readily and thoroughly absorbed by this method. It is also commonly applied when administering:
- Cardiovascular Drugs
Many substances are absorbed sublingually. However, not all substances are permeable and accessible to the mucous membrane, which may function as a barrier preventing effective diffusion. MigraSpray’s micro-spray technology ensures that the sublingual mucous membrane is an ideal site for such absorption.
This route of absorption bypasses the gastrointestinal tract and requires only small dosages of the active ingredients contained in MigraSpray. It then allows the formula to achieve rapid absorption, reduced degradation, and enhanced effectiveness with no reported side effects. More than that, it also serves to avoid unpleasant gastric symptoms in individuals that suffer from a variety of gastrointestinal difficulties such as:
- Hyperactive Gut
- Celiac Disease
- Compromised Digestion
Lea, L. (2002, April 21). Sublingual Absorption. Positive Health Complimentary Medicine Magazine.
Calabrese Ph.D., E. J. and Baldwin, L. A. (1998). Developing Insights on the Nature of the Dose-Response Relationship in the Low Dose Zone: Hormesis as a Biological Hypothesis. Biomedical Therapy, Vol. XVI, No. 3, 235-240.